Estimating long-term treatment effects without long-term outcome data
David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)
GPI Working Paper No. 13-2023
The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.
Other working papers
Longtermist institutional reform – Tyler M. John (Rutgers University) and William MacAskill (Global Priorities Institute, Oxford University)
There is a vast number of people who will live in the centuries and millennia to come. Even if homo sapiens survives merely as long as a typical species, we have hundreds of thousands of years ahead of us. And our future potential could be much greater than that again: it will be hundreds of millions of years until the Earth is sterilized by the expansion of the Sun, and many trillions of years before the last stars die out. …
Consequentialism, Cluelessness, Clumsiness, and Counterfactuals – Alan Hájek (Australian National University)
According to a standard statement of objective consequentialism, a morally right action is one that has the best consequences. More generally, given a choice between two actions, one is morally better than the other just in case the consequences of the former action are better than those of the latter. (These are not just the immediate consequences of the actions, but the long-term consequences, perhaps until the end of history.) This account glides easily off the tongue—so easily that…
Three mistakes in the moral mathematics of existential risk – David Thorstad (Global Priorities Institute, University of Oxford)
Longtermists have recently argued that it is overwhelmingly important to do what we can to mitigate existential risks to humanity. I consider three mistakes that are often made in calculating the value of existential risk mitigation: focusing on cumulative risk rather than period risk; ignoring background risk; and neglecting population dynamics. I show how correcting these mistakes pushes the value of existential risk mitigation substantially below leading estimates, potentially low enough to…