Estimating long-term treatment effects without long-term outcome data
David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)
GPI Working Paper No. 13-2023
The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.
Other working papers
The evidentialist’s wager – William MacAskill, Aron Vallinder (Global Priorities Institute, Oxford University) Caspar Österheld (Duke University), Carl Shulman (Future of Humanity Institute, Oxford University), Johannes Treutlein (TU Berlin)
Suppose that an altruistic and morally motivated agent who is uncertain between evidential decision theory (EDT) and causal decision theory (CDT) finds herself in a situation in which the two theories give conflicting verdicts. We argue that even if she has significantly higher credence in CDT, she should nevertheless act …
Longtermist institutional reform – Tyler M. John (Rutgers University) and William MacAskill (Global Priorities Institute, Oxford University)
There is a vast number of people who will live in the centuries and millennia to come. Even if homo sapiens survives merely as long as a typical species, we have hundreds of thousands of years ahead of us. And our future potential could be much greater than that again: it will be hundreds of millions of years until the Earth is sterilized by the expansion of the Sun, and many trillions of years before the last stars die out. …
Is Existential Risk Mitigation Uniquely Cost-Effective? Not in Standard Population Models – Gustav Alexandrie (Global Priorities Institute, University of Oxford) and Maya Eden (Brandeis University)
What socially beneficial causes should philanthropists prioritize if they give equal ethical weight to the welfare of current and future generations? Many have argued that, because human extinction would result in a permanent loss of all future generations, extinction risk mitigation should be the top priority given this impartial stance. Using standard models of population dynamics, we challenge this conclusion. We first introduce a theoretical framework for quantifying undiscounted cost-effectiveness over…