Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

On two arguments for Fanaticism – Jeffrey Sanford Russell (University of Southern California)

Should we make significant sacrifices to ever-so-slightly lower the chance of extremely bad outcomes, or to ever-so-slightly raise the chance of extremely good outcomes? Fanaticism says yes: for every bad outcome, there is a tiny chance of of extreme disaster that is even worse, and for every good outcome, there is a tiny chance of an enormous good that is even better.

The weight of suffering – Andreas Mogensen (Global Priorities Institute, University of Oxford)

How should we weigh suffering against happiness? This paper highlights the existence of an argument from intuitively plausible axiological principles to the striking conclusion that in comparing different populations, there exists some depth of suffering that cannot be compensated for by any measure of well-being. In addition to a number of structural principles, the argument relies on two key premises. The first is the contrary of the so-called Reverse Repugnant Conclusion…

How to resist the Fading Qualia Argument – Andreas Mogensen (Global Priorities Institute, University of Oxford)

The Fading Qualia Argument is perhaps the strongest argument supporting the view that in order for a system to be conscious, it does not need to be made of anything in particular, so long as its internal parts have the right causal relations to each other and to the system’s inputs and outputs. I show how the argument can be resisted given two key assumptions: that consciousness is associated with vagueness at its boundaries and that conscious neural activity has a particular kind of holistic structure. …