Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Paris School of Economics)

GPI Working Paper No. 11-2020

This paper has been awarded the paper prize of the 2019 Early Career Conference Programme.

Estimating long-term impacts of actions is important in many areas but the key difficulty is that long-term outcomes are only observed with a long delay. One alternative approach is to measure the effect on an intermediate outcome or a statistical surrogate and then use this to estimate the long-term effect. Athey et al. (2019) generalise the surrogacy method to work with multiple surrogates, rather than just one, increasing its credibility in social science contexts. I empirically test the multiple surrogates approach for long-term effect estimation in real-world conditions using long-run RCTs from development economics. In the context of conditional cash transfers for education in Colombia, I find that the method works well for predicting treatment effects over a 5-year time span but poorly over 10 years due to a reduced set of variables available when attempting to predict effects further into the future. The method is sensitive to observing appropriate surrogates.

Other working papers

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Sometimes, one decision can guarantee that a risky event will happen. For instance, it only took one team of researchers to synthesize and publish the horsepox genome, thus imposing its publication even though other researchers might have refrained for biosecurity reasons. We examine cases where everybody who can impose a given event has the same goal but different information about whether the event furthers that goal. …

Longtermist institutional reform – Tyler M. John (Rutgers University) and William MacAskill (Global Priorities Institute, Oxford University)

There is a vast number of people who will live in the centuries and millennia to come. Even if homo sapiens survives merely as long as a typical species, we have hundreds of thousands of years ahead of us. And our future potential could be much greater than that again: it will be hundreds of millions of years until the Earth is sterilized by the expansion of the Sun, and many trillions of years before the last stars die out. …

Dispelling the Anthropic Shadow – Teruji Thomas (Global Priorities Institute, University of Oxford)

There are some possible events that we could not possibly discover in our past. We could not discover an omnicidal catastrophe, an event so destructive that it permanently wiped out life on Earth. Had such a catastrophe occurred, we wouldn’t be here to find out. This space of unobservable histories has been called the anthropic shadow. Several authors claim that the anthropic shadow leads to an ‘observation selection bias’, analogous to survivorship bias, when we use the historical record to estimate catastrophic risks. …