Estimating long-term treatment effects without long-term outcome data
David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)
GPI Working Paper No. 13-2023
The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.
Other working papers
Philosophical considerations relevant to valuing continued human survival: Conceptual Analysis, Population Axiology, and Decision Theory – Andreas Mogensen (Global Priorities Institute, University of Oxford)
Many think that human extinction would be a catastrophic tragedy, and that we ought to do more to reduce extinction risk. There is less agreement on exactly why. If some catastrophe were to kill everyone, that would obviously be horrific. Still, many think the deaths of billions of people don’t exhaust what would be so terrible about extinction. After all, we can be confident that billions of people are going to die – many horribly and before their time – if humanity does not go extinct. …
The epistemic challenge to longtermism – Christian Tarsney (Global Priorities Institute, Oxford University)
Longtermists claim that what we ought to do is mainly determined by how our actions might affect the very long-run future. A natural objection to longtermism is that these effects may be nearly impossible to predict— perhaps so close to impossible that, despite the astronomical importance of the far future, the expected value of our present actions is mainly determined by near-term considerations. This paper aims to precisify and evaluate one version of this epistemic objection to longtermism…
High risk, low reward: A challenge to the astronomical value of existential risk mitigation – David Thorstad (Global Priorities Institute, University of Oxford)
Many philosophers defend two claims: the astronomical value thesis that it is astronomically important to mitigate existential risks to humanity, and existential risk pessimism, the claim that humanity faces high levels of existential risk. It is natural to think that existential risk pessimism supports the astronomical value thesis. In this paper, I argue that precisely the opposite is true. Across a range of assumptions, existential risk pessimism significantly reduces the value of existential risk mitigation…