Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

Imperfect Recall and AI Delegation – Eric Olav Chen (Global Priorities Institute, University of Oxford), Alexis Ghersengorin (Global Priorities Institute, University of Oxford) and Sami Petersen (Department of Economics, University of Oxford)

A principal wants to deploy an artificial intelligence (AI) system to perform some task. But the AI may be misaligned and aim to pursue a conflicting objective. The principal cannot restrict its options or deliver punishments. Instead, the principal is endowed with the ability to impose imperfect recall on the agent. The principal can then simulate the task and obscure whether it is real or part of a test. This allows the principal to screen misaligned AIs during testing and discipline their behaviour in deployment. By increasing the…

Non-additive axiologies in large worlds – Christian Tarsney and Teruji Thomas (Global Priorities Institute, Oxford University)

Is the overall value of a world just the sum of values contributed by each value-bearing entity in that world? Additively separable axiologies (like total utilitarianism, prioritarianism, and critical level views) say ‘yes’, but non-additive axiologies (like average utilitarianism, rank-discounted utilitarianism, and variable value views) say ‘no’…

Meaning, medicine and merit – Andreas Mogensen (Global Priorities Institute, Oxford University)

Given the inevitability of scarcity, should public institutions ration healthcare resources so as to prioritize those who contribute more to society? Intuitively, we may feel that this would be somehow inegalitarian. I argue that the egalitarian objection to prioritizing treatment on the basis of patients’ usefulness to others is best thought…