Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

Minimal and Expansive Longtermism – Hilary Greaves (University of Oxford) and Christian Tarsney (Population Wellbeing Initiative, University of Texas at Austin)

The standard case for longtermism focuses on a small set of risks to the far future, and argues that in a small set of choice situations, the present marginal value of mitigating those risks is very great. But many longtermists are attracted to, and many critics of longtermism worried by, a farther-reaching form of longtermism. According to this farther-reaching form, there are many ways of improving the far future, which determine the value of our options in all or nearly all choice situations…

In search of a biological crux for AI consciousness – Bradford Saad (Global Priorities Institute, University of Oxford)

Whether AI systems could be conscious is often thought to turn on whether consciousness is closely linked to biology. The rough thought is that if consciousness is closely linked to biology, then AI consciousness is impossible, and if consciousness is not closely linked to biology, then AI consciousness is possible—or, at any rate, it’s more likely to be possible. A clearer specification of the kind of link between consciousness and biology that is crucial for the possibility of AI consciousness would help organize inquiry into…

Doomsday rings twice – Andreas Mogensen (Global Priorities Institute, Oxford University)

This paper considers the argument according to which, because we should regard it as a priori very unlikely that we are among the most important people who will ever exist, we should increase our confidence that the human species will not persist beyond the current historical era, which seems to represent…