Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

Aggregating Small Risks of Serious Harms – Tomi Francis (Global Priorities Institute, University of Oxford)

According to Partial Aggregation, a serious harm can be outweighed by a large number of somewhat less serious harms, but can outweigh any number of trivial harms. In this paper, I address the question of how we should extend Partial Aggregation to cases of risk, and especially to cases involving small risks of serious harms. I argue that, contrary to the most popular versions of the ex ante and ex post views, we should sometimes prevent a small risk that a large number of people will suffer serious harms rather than prevent…

How important is the end of humanity? Lay people prioritize extinction prevention but not above all other societal issues. – Matthew Coleman (Northeastern University), Lucius Caviola (Global Priorities Institute, University of Oxford) et al.

Human extinction would mean the deaths of eight billion people and the end of humanity’s achievements, culture, and future potential. On several ethical views, extinction would be a terrible outcome. How do people think about human extinction? And how much do they prioritize preventing extinction over other societal issues? Across six empirical studies (N = 2,541; U.S. and China) we find that people consider extinction prevention a global priority and deserving of greatly increased societal resources. …

The scope of longtermism – David Thorstad (Global Priorities Institute, University of Oxford)

Longtermism holds roughly that in many decision situations, the best thing we can do is what is best for the long-term future. The scope question for longtermism asks: how large is the class of decision situations for which longtermism holds? Although longtermism was initially developed to describe the situation of…