Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

In search of a biological crux for AI consciousness – Bradford Saad (Global Priorities Institute, University of Oxford)

Whether AI systems could be conscious is often thought to turn on whether consciousness is closely linked to biology. The rough thought is that if consciousness is closely linked to biology, then AI consciousness is impossible, and if consciousness is not closely linked to biology, then AI consciousness is possible—or, at any rate, it’s more likely to be possible. A clearer specification of the kind of link between consciousness and biology that is crucial for the possibility of AI consciousness would help organize inquiry into…

Longtermist institutional reform – Tyler M. John (Rutgers University) and William MacAskill (Global Priorities Institute, Oxford University)

There is a vast number of people who will live in the centuries and millennia to come. Even if homo sapiens survives merely as long as a typical species, we have hundreds of thousands of years ahead of us. And our future potential could be much greater than that again: it will be hundreds of millions of years until the Earth is sterilized by the expansion of the Sun, and many trillions of years before the last stars die out. …

Can an evidentialist be risk-averse? – Hayden Wilkinson (Global Priorities Institute, University of Oxford)

Two key questions of normative decision theory are: 1) whether the probabilities relevant to decision theory are evidential or causal; and 2) whether agents should be risk-neutral, and so maximise the expected value of the outcome, or instead risk-averse (or otherwise sensitive to risk). These questions are typically thought to be independent – that our answer to one bears little on our answer to the other. …