Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

Existential Risk and Growth – Philip Trammell (Global Priorities Institute and Department of Economics, University of Oxford) and Leopold Aschenbrenner

Technologies may pose existential risks to civilization. Though accelerating technological development may increase the risk of anthropogenic existential catastrophe per period in the short run, two considerations suggest that a sector-neutral acceleration decreases the risk that such a catastrophe ever occurs. First, acceleration decreases the time spent at each technology level. Second, since a richer society is willing to sacrifice more for safety, optimal policy can yield an “existential risk Kuznets curve”; acceleration…

The paralysis argument – William MacAskill, Andreas Mogensen (Global Priorities Institute, Oxford University)

Given plausible assumptions about the long-run impact of our everyday actions, we show that standard non-consequentialist constraints on doing harm entail that we should try to do as little as possible in our lives. We call this the Paralysis Argument. After laying out the argument, we consider and respond to…

Will AI Avoid Exploitation? – Adam Bales (Global Priorities Institute, University of Oxford)

A simple argument suggests that we can fruitfully model advanced AI systems using expected utility theory. According to this argument, an agent will need to act as if maximising expected utility if they’re to avoid exploitation. Insofar as we should expect advanced AI to avoid exploitation, it follows that we should expected advanced AI to act as if maximising expected utility. I spell out this argument more carefully and demonstrate that it fails, but show that the manner of its failure is instructive…