Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

The Hinge of History Hypothesis: Reply to MacAskill – Andreas Mogensen (Global Priorities Institute, University of Oxford)

Some believe that the current era is uniquely important with respect to how well the rest of human history goes. Following Parfit, call this the Hinge of History Hypothesis. Recently, MacAskill has argued that our era is actually very unlikely to be especially influential in the way asserted by the Hinge of History Hypothesis. I respond to MacAskill, pointing to important unresolved ambiguities in his proposed definition of what it means for a time to be influential and criticizing the two arguments…

Are we living at the hinge of history? – William MacAskill (Global Priorities Institute, Oxford University)

In the final pages of On What Matters, Volume II, Derek Parfit comments: ‘We live during the hinge of history… If we act wisely in the next few centuries, humanity will survive its most dangerous and decisive period… What now matters most is that we avoid ending human history.’ This passage echoes Parfit’s comment, in Reasons and Persons, that ‘the next few centuries will be the most important in human history’. …

Will AI Avoid Exploitation? – Adam Bales (Global Priorities Institute, University of Oxford)

A simple argument suggests that we can fruitfully model advanced AI systems using expected utility theory. According to this argument, an agent will need to act as if maximising expected utility if they’re to avoid exploitation. Insofar as we should expect advanced AI to avoid exploitation, it follows that we should expected advanced AI to act as if maximising expected utility. I spell out this argument more carefully and demonstrate that it fails, but show that the manner of its failure is instructive…