Estimating long-term treatment effects without long-term outcome data

David Rhys Bernard (Rethink Priorities), Jojo Lee and Victor Yaneng Wang (Global Priorities Institute, University of Oxford)

GPI Working Paper No. 13-2023

The surrogate index method allows policymakers to estimate long-run treatment effects before long-run outcomes are observable. We meta-analyse this approach over nine long-run RCTs in development economics, comparing surrogate estimates to estimates from actual long-run RCT outcomes. We introduce the M-lasso algorithm for constructing the surrogate approach’s first-stage predictive model and compare its performance with other surrogate estimation methods. Across methods, we find a negative bias in surrogate estimates. For the M-lasso method, in particular, we investigate reasons for this bias and quantify significant precision gains. This provides evidence that the surrogate index method incurs a bias-variance trade-off.

Other working papers

High risk, low reward: A challenge to the astronomical value of existential risk mitigation – David Thorstad (Global Priorities Institute, University of Oxford)

Many philosophers defend two claims: the astronomical value thesis that it is astronomically important to mitigate existential risks to humanity, and existential risk pessimism, the claim that humanity faces high levels of existential risk. It is natural to think that existential risk pessimism supports the astronomical value thesis. In this paper, I argue that precisely the opposite is true. Across a range of assumptions, existential risk pessimism significantly reduces the value of existential risk mitigation…